MotivationExperiments in which the effect of combined manipulations is compared with the effects of their pure constituents have received a great deal of attention.Examples include the study of combination therapies and the comparison of double and single knockout model organisms.Often the effect of the FRUIT combined manipulation is not a mere add
The study of the effect of large-scale drivers (e.g., climate) of human diseases typically relies on aggregate disease data collected by the government surveillance network.The usual approach to analyze these data, however, often ignores a) changes in the total number of individuals examined, b) the bias towards symptomatic individuals in routine g
A curvilinear finite element of the median line of an axisymmetrically loaded shell of revolution with a stiffness matrix of $8{ imes} 8$ size is used when choosing nodal unknowns in the form of displacements and their first derivatives is used.The constitutive equations at the loading step are implemented in two versions.In the first version, the
Abstract Traditional Chinese names are composed of three parts: the family name, a generation name, and a given name.The male generation name marks the position of the bearer in the sequence of generations within a clan.Until the middle of the 20th century, most Chinese men used their generation names regularly.Since then the Hubcap use of generati